Detailed Product Description
Common name: fipronil Chemical name: 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile Molecular formula: C12H4Cl2F6N4OS Chemical class: phenyl pyrazole insecticide CAS no.: 120068-37-3 Properties: Form: white powder Molecular weight: 437.2 Melting point: 195.5-2030C Vapour pressure: 3.7 x 10-4MPa Solubility in water: 1.9mg/L (pH 7) Solubility in solvents: acetone 546g/ L, methanol 137.5g/ L, toluene 300g/ L Stability: stable in water at pH 5 and pH 7; slowly hydrolysed at pH 9. Stable to heat. Slowly degrades in sunlight Toxicity: Acute oral LD50 for rats: 97mg/kg Acute dermal LD50 for rats: >2,000mg/kg Inhalation LC50 for rats: 0.682mg/L No irritation to eyes and skin Non-mutagenic, non-teratogenic, non-carcinogenic Ecotoxicology: Effects on aquatic organisms: cyprinoid LC50 30μg/l, bulltrout LC50 248μg/l(96h), daphnia EC50 190μg/l(48h), algae EC50 60μg/l. High toxic to shrimps and crabs Effects on bees: LD50 4.17 x 10-3μg/bee Effects on birds: mallard ducks LD50>2,000mg/kg, bobwhite quail 11.1mg/kg Effects on earthworm: not toxic Environmental fate: field persistence is low-moderate in water and soil (half-life 10-130h, in water and 45-530h in soil) with three major depredates formed in soil Mode of action: Fipronil is an extremely active molecule and is a potent disruptor of the insect central nervous system via the aminobutyric acid (GABA) regulated chloride channel. Despite the fact that the GABA channel is important in nerve transmission in both vertebrate and invertebrate animals, and that fipronil does bind to the GABA receptor in vertebrates, the binding is "less tight" which offers a degree of selectivity. Usage: Fipronil is used against major lepidopterous and orthopterous pests on a wide range of field and horticultural crops and against coleopterous larvae in soils. It is also employed for cockroach, ant control and also used against pests of field corn, golf courses and commercial turf.
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